Surgical Case Reports

Humoral Hypercalcemia of Malignancy Caused by Parathyroid Hormone-Related Protein-Secreting Medullary Thyroid Carcinoma: A Case Report

Takuya Hirose, et al.

INTRODUCTION: Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor arising from the parafollicular C cells, accounting for approximately 1.5% of all thyroid cancers. Although calcitonin secreted by the MTC typically lowers calcium levels, serum calcium concentrations usually remain within the normal range due to compensatory parathyroid hormone (PTH) secretion. Hypercalcemia of malignancy is broadly categorized as humoral hypercalcemia of malignancy (HHM), mediated by parathyroid hormone-related protein (PTHrP), or local osteolytic hypercalcemia. We report a rare case of HHM caused by a PTHrP-secreting MTC.

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BRCA2 Reversion Mutation after Neoadjuvant Dose-Dense EC and Dose-Dense Paclitaxel in Triple-Negative Breast Cancer: A Case Report and Literature Review

Hajime Hikino, et al.

INTRODUCTION: BRCA reversion mutations are known mechanisms of acquired resistance to poly (ADP-ribose) polymerase inhibitors (PARPis) and platinum agents. However, their clinical emergence without such therapies is rarely reported.

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Surgical Treatment for Bacteremia due to Translocation of Enterococcus gallinarum: A Case Report

Yoshitaka Imoto, et al.

INTRODUCTION: Bacterial translocation (BT) followed by bacteremia is usually managed with antibiotics, but some cases remain refractory. Herein, we report an immunocompromised patient with bacteremia due to the translocation of Enterococcus gallinarum, a rare pathogen among enterococcal infections, who was successfully treated with surgical intervention.

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Adult Primary Hepatic Sarcoma Presenting as a Chronic Expanding Hematoma

Takako Yamada Fujii, et al.

INTRODUCTION: Primary hepatic sarcoma is extremely rare in adults and can be difficult to distinguish from benign hemorrhagic lesions on imaging. We report a rare case of undifferentiated sarcoma (US) that initially mimicked chronic expanding hematoma (CEH) and ruptured.

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Single-Incision Laparoscopic Cholecystectomy in a Patient with a Left Ventricular Assist Device

Ayako Ishii, et al.

INTRODUCTION: Laparoscopic cholecystectomy (LC) is the standard treatment for benign gallbladder diseases, including acute cholecystitis (AC). However, performing LC in patients with a left ventricular assist device (LVAD) presents specific technical and physiological challenges related to driveline preservation and hemodynamic stability. We report the first case of single-incision laparoscopic cholecystectomy (SILC) via the right lower abdomen in a patient with an LVAD after treatment for biliary tract infection, following prior surgery for strangulated ileus and umbilical wound infection.

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Two Cases of Intraductal Papilloma with Sebaceous Metaplasia of the Breast

Kurumi Okada, et al.

INTRODUCTION: Intraductal papilloma is a common benign breast lesion that typically presents with nipple discharge or a palpable mass. While apocrine metaplasia is frequently observed, sebaceous metaplasia is very rare in breast lesions, with only a few cases reported to date. We herein describe two surgically resected cases of intraductal papilloma with sebaceous metaplasia, both of which were histologically proven benign following imaging findings that were suspicious for malignancy.

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Laparoscopic Cholecystectomy in a Patient with Low-Lying Costal Arch due to Ankylosing Spondylitis: A Case Report

Tomoyuki Fukami, et al.

INTRODUCTION: Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the sacroiliac joints and spine, which can lead to bony ankylosis during the healing process. The prevalence of AS in the Japanese population is relatively low, and encounters with such patients in routine clinical practice are uncommon.

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Semi-Urgent Totally Extraperitoneal Repair for Inguinal Hernia Causing Insufficient Intraperitoneal Exchange in a Patient on Peritoneal Dialysis: A Case Report

Yume Yabu, et al.

INTRODUCTION: Inguinal hernias are mechanical complications in patients undergoing peritoneal dialysis (PD) that may threaten the continuation of PD. Herein, we report a rare case in which PD could not be completed owing to outflow failure associated with a large inguinal hernia that was successfully managed with semi-urgent totally extraperitoneal (TEP) repair.

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Spontaneous Regression of Metastatic Colorectal Cancer Following Discontinuation of an Interleukin-6 Receptor Inhibitor: A Case Report

Eiki Miyake, et al.

Abstract INTRODUCTION: Spontaneous cancer regression is exceptionally rare, particularly in colorectal cancer. Tumor regression has been reported in some patients with autoimmune diseases or organ transplants, after cessation of immunosuppressive therapy; however, its underlying mechanisms remain unclear. We report a rare case of Stage IVA transverse colon cancer with synchronous liver metastasis that showed complete pathological regression in both sites after discontinuation of tocilizumab, an interleukin-6 receptor inhibitor.

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Endometriosis-Associated Intestinal Tumor: A Case Report and Literature Review with Comprehensive Proteomic Data

Naoyuki Toyota, et al.

INTRODUCTION: Endometriosis-associated intestinal tumors (EAITs) are rare malignancies that arise from ectopic endometrial tissue, and their clinical and molecular characteristics remain poorly defined.

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Disseminated Mucormycosis with Characteristic Gastric Ulcers and Extensive Intravascular Invasion after ABO-Incompatible Living-Donor Liver Transplantation: A Case Report

Satoshi Takada, et al.

INTRODUCTION: Mucormycosis is a life-threatening invasive fungal infection that occurs mainly in patients who are immunocompromised. Here, we report a case of mucormycosis with characteristic gastric ulcers and severe vascular invasion after ABO-incompatible living-donor liver transplantation.

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Safe Resection of a Giant Mediastinal Liposarcoma with Severe Cardiac Compression

Kazuhiro Mizota, et al.

INTRODUCTION: Dedifferentiated liposarcomas of the mediastinum are exceedingly rare, and surgical resection is the primary treatment of choice. Mediastinal mass syndrome (MMS) is an oncological emergency characterized by compression or invasion of the heart, great vessels, or trachea by a large mediastinal tumor, particularly during the induction of anesthesia. We report a case of a giant dedifferentiated liposarcoma in the anterior mediastinum, surgically resected due to severe cardiac compression and presenting as an oncological emergency.

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